Tamoxifen

Tamoxifen

Strength: 10 mg
Quantity: 100 tablets
Active substance: tamoxifen
Manufacturer: Magnus Pharmaceuticals

Indications:

• Primarily used in the treatment of hormone receptor-positive breast cancer in women.
• Often prescribed as part of adjuvant therapy following surgery to reduce the risk of cancer recurrence.
• Used off-label for other conditions, such as gynecomastia in men and fertility issues in women.

Mechanism of Action: Tamoxifen is a selective estrogen receptor modulator (SERM). It binds to estrogen receptors in breast tissue, blocking the effects of estrogen, which can fuel the growth of certain types of breast cancer. This action helps to slow or stop the growth of tumors.

Dosage:

• Typical dosing for breast cancer treatment is usually 20 mg per day, which may be adjusted based on individual response and medical advice.
• Treatment duration can vary, often lasting 5 to 10 years.

Side Effects:

• Potential side effects include hot flashes, nausea, fatigue, and changes in menstrual cycles.
• There may also be an increased risk of blood clots and endometrial cancer.

Precautions:

• Not recommended for individuals with a history of blood clots, liver disease, or uterine cancer.
• Regular monitoring by a healthcare provider is essential during treatment.

Legal Status: Tamoxifen is available by prescription in many countries and is a standard treatment in oncology.

Storage: Store in a cool, dry place away from direct sunlight and out of reach of children.

Conclusion

Tamoxifen citrate is a crucial medication in the management of hormone receptor-positive breast cancer. While effective, it should be used under the supervision of a healthcare provider to monitor for side effects and ensure optimal treatment outcomes.