Proviron is a purely androgenic steroid with no anabolic qualities. The drug was used both as an anti-estrogen that “prevents” estrogen from being produced through the aromatization of sex steroids, and for its hardening effect upon musculature. Unlike Nolvadex (which only keeps estrogen from bonding with its receptors by blocking them), Proviron actually prevents the formation of estrogen. Due to lower estrogen levels, athletes retained less water and prevented (for the most part) the formation of gynecomastia and female pattern fat deposits.
Proviron was popular as a post-cycle anti-estrogen. (To keep estrogen from becoming the dominant hormone and to kick up sex drive lost due to low androgen levels) In fact, it is used in medicine as a drug to increase sperm production and eliminate sexual dysfunction in males. In some cases Proviron is prescribed to decrease flow or stop menstruation in females. For males this only replaces the androgens levels, not cures the problems of low testosterone production. Though the reader should note that the decrease in circulatory estrogen in itself promotes increased HPTA activity. At one time Proviron was commonly used year round by many appearance oriented athletes to maintain hardness. Now, according to recent polls, more athletes are using ephedrine and Clenbuterol to replaced Proviron for this purpose. By the way, frequent and sometimes painful erections are side effects of Proviron use. (So?)
Proviron possesses the ability to bind SHBG at a high rate. By doing so other co-administered AAS (or endogenous testosterone) remained in an unbound/free state. This resulted in greater anabolic and androgenic activity realization with lower dosage requirements.
Administration (Men):
To treat androgen insufficiency, mesterolone is usually given in a dose of 1 tablet (25 mg) three times per day at the initiation of therapy. The drug is later continued at a lower maintenance dose, which usually consists of taking 1 tablet (25 mg) one to two times per day. Similar doses are used to support male fertility, usually in conjunction with other fertility drugs like injectable FSH. The usual dosage among male athletes is between 50 mg and 150 mg of mesterolone per day, or two to six 25 mg tablets. The drug is typically taken in cycles of 6-12 weeks in length, which is usually a sufficient period of time to notice the benefits of drug therapy.
Many bodybuilders favor the use of mesterolone during dieting phases or contest preparation, when low estrogen and high androgen levels are particularly desirable. This is especially beneficial when anabolics like Winstrol, Anavar, or Primobolan are being used alone, as the androgenic content of these drugs is relatively low. Mesterolone can be effectively used here to adjust the androgen to estrogen ratio upwards, bringing about an increase in the hardness and density of the muscles, supporting libido and general sense of well being, and increasing the tendency to burn body fat. It is also commonly used (at a similar dosage) to prevent gynecomastia when other aromatizable steroids are being administered, often in conjunction with 10-20 mg per day of Nolvadex.
