Genotropin 36iu

Genotropin 36iu

• Substance: Somatropin
• Quantity: 12mg (36 IU)
• Manufacturer: Pfizer Labs

Genotropin is a brand name for somatropin, which is a synthetic form of human growth hormone (hGH) used to treat growth disorders and conditions caused by a deficiency in growth hormone. It is manufactured by Pfizer and is typically used in both pediatric and adult patients.

Genotropin 36 IU is a 36 International Unit (IU) cartridge of somatropin, which is designed for use with a Genotropin pen for subcutaneous injection.

Product Features:

• Formulation: Genotropin 36 IU contains somatropin, a recombinant version of the human growth hormone. Somatropin is identical to the natural growth hormone produced by the pituitary gland.
• Appearance: The product is presented in a sterile lyophilized (freeze-dried) powder that must be reconstituted with the accompanying diluent before administration.
• Storage: The product must be stored in a refrigerator (2–8°C or 36–46°F) and should not be frozen. Once reconstituted, it should be used within 28 days if kept in the fridge.
• Dosage: Genotropin dosing is individualized based on the patient’s age, body weight, and medical condition. Doses are typically administered subcutaneously (under the skin) once daily or several times a week, depending on the specific indication.

Indications:

Genotropin is prescribed for:

• Growth Hormone Deficiency (GHD): In both children and adults with diagnosed GHD.
• Turner Syndrome: A genetic condition that results in short stature and other physical anomalies.
• Chronic Kidney Disease: In children with growth failure due to kidney disease.
• Prader-Willi Syndrome: A genetic disorder leading to short stature and obesity.
• Small for Gestational Age (SGA): Children who were born small for gestational age and have not caught up with growth by the age of 2.
• Idiopathic Short Stature: Children who are significantly shorter than their peers without a known cause.

Mechanism of Action:

Genotropin works by stimulating the growth of tissues and bones. It does so by promoting the production of proteins and other factors that support growth, including insulin-like growth factor 1 (IGF-1), which is primarily produced in the liver in response to growth hormone.

Administration:

• Genotropin Pen: The 36 IU cartridge is designed to be used with a Genotropin Pen device. This pen allows for precise dosing and is easier for patients to use, particularly for those who require daily or frequent injections.
• Reconstitution: The powder must be reconstituted with sterile water before being injected. Always follow the manufacturer’s instructions on how to properly prepare and administer the medication.

Side Effects:

Common side effects include:

• Injection site reactions (pain, redness, swelling)
• Headache
• Muscle pain or joint pain
• Edema (swelling)
• Increased blood sugar levels (hyperglycemia)
• Carpal tunnel syndrome

Rare but serious side effects may include:

• Intracranial hypertension (increased pressure in the brain)
• Severe allergic reactions
• Numbness, tingling, or weakness in the arms or legs

Precautions:

• Allergy: Genotropin should not be used if you are allergic to any ingredient in the product.
• Pre-existing medical conditions: It is important to inform your healthcare provider if you have a history of cancer, diabetes, or any underlying medical conditions.
• Children and Adolescents: The use of growth hormone in children requires monitoring for growth progress, side effects, and other health parameters.

Packaging:

Genotropin 36 IU typically comes as a 36 IU cartridge for use with the Genotropin Pen, along with diluent, and instructions for reconstitution. The packaging also includes a patient information leaflet for detailed instructions on proper use.