Exemestane

Exemestane is a medication classified as an aromatase inhibitor, primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by lowering estrogen levels in the body, which can help slow or stop the growth of certain types of breast tumors that require estrogen to grow.

Key Features:

• Indication: Approved for the treatment of early-stage and metastatic breast cancer in postmenopausal women.
• Dosage Form: Typically available as oral tablets (25 mg).
• Mechanism of Action: Irreversibly inhibits the aromatase enzyme, which is responsible for converting androgens to estrogens, effectively reducing estrogen production.

Benefits:

• Effective Treatment: Shown to reduce the risk of cancer recurrence and improve overall survival rates in suitable patients.
• Improved Tolerance: Generally well-tolerated compared to some other treatments.

Considerations:

• Side Effects: Possible side effects may include hot flashes, fatigue, joint pain, and increased risk of osteoporosis.
• Monitoring: Regular follow-up with a healthcare provider is essential to monitor for side effects and assess treatment effectiveness.
• Contraindications: Not recommended for use in premenopausal women or during pregnancy.

Always consult with a healthcare professional for personalized advice and monitoring while using exemestane.